|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0016360,
umls-concept:C0030705,
umls-concept:C0040808,
umls-concept:C0045093,
umls-concept:C0205179,
umls-concept:C0205420,
umls-concept:C0332174,
umls-concept:C0346647,
umls-concept:C0348013,
umls-concept:C0574032,
umls-concept:C0600688,
umls-concept:C0920321,
umls-concept:C1512162,
umls-concept:C1517927,
umls-concept:C1522449
|
|
pubmed:issue |
19
|
|
pubmed:dateCreated |
2000-10-18
|
|
pubmed:abstractText |
We performed a phase I trial of protracted venous infusion (PVI) fluorouracil (5-FU) plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer to determine the maximum-tolerated dose of gemcitabine that could be safely administered. We also sought to identify the toxicities associated with this treatment protocol.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0732-183X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
18
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
3384-9
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:11013279-Adenocarcinoma,
pubmed-meshheading:11013279-Aged,
pubmed-meshheading:11013279-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:11013279-Combined Modality Therapy,
pubmed-meshheading:11013279-Deoxycytidine,
pubmed-meshheading:11013279-Dose-Response Relationship, Drug,
pubmed-meshheading:11013279-Dose-Response Relationship, Radiation,
pubmed-meshheading:11013279-Drug Administration Schedule,
pubmed-meshheading:11013279-Female,
pubmed-meshheading:11013279-Fluorouracil,
pubmed-meshheading:11013279-Humans,
pubmed-meshheading:11013279-Infusions, Intravenous,
pubmed-meshheading:11013279-Male,
pubmed-meshheading:11013279-Middle Aged,
pubmed-meshheading:11013279-Pancreatic Neoplasms,
pubmed-meshheading:11013279-Radiotherapy,
pubmed-meshheading:11013279-Survival Analysis
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Eastern Cooperative Oncology Group Phase I trial of protracted venous infusion fluorouracil plus weekly gemcitabine with concurrent radiation therapy in patients with locally advanced pancreas cancer: a regimen with unexpected early toxicity.
|
|
pubmed:affiliation |
Northwestern University Medical School, Chicago, IL, USA. mtalamonti@nmff.org
|
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, P.H.S.,
Clinical Trial, Phase I
|
