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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-10-27
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pubmed:abstractText |
As an experimental analogue of human focal glomerular sclerosis (FGS), adriamycin (ADR)-induced nephropathy is well-characterized in rats. Previously, this model has not been fully established in mice. The extension of this model to the mouse would be useful in the application of genetic and monoclonal antibody technology to characterize mechanisms of progressive renal disease. Herein, we describe a stable and reproducible murine model of chronic proteinuria induced by ADR.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1797-804
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11012915-Animals,
pubmed-meshheading:11012915-Antibodies, Monoclonal,
pubmed-meshheading:11012915-Antineoplastic Agents,
pubmed-meshheading:11012915-CD4-Positive T-Lymphocytes,
pubmed-meshheading:11012915-CD8-Positive T-Lymphocytes,
pubmed-meshheading:11012915-Disease Models, Animal,
pubmed-meshheading:11012915-Doxorubicin,
pubmed-meshheading:11012915-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:11012915-Kidney Glomerulus,
pubmed-meshheading:11012915-Male,
pubmed-meshheading:11012915-Mice,
pubmed-meshheading:11012915-Mice, Inbred BALB C,
pubmed-meshheading:11012915-Mice, Inbred C57BL,
pubmed-meshheading:11012915-Microscopy, Electron,
pubmed-meshheading:11012915-Proteinuria,
pubmed-meshheading:11012915-Telefacsimile
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pubmed:year |
2000
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pubmed:articleTitle |
Progressive adriamycin nephropathy in mice: sequence of histologic and immunohistochemical events.
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pubmed:affiliation |
Department of Renal Medicine, University of Sydney at Westmead Hospital, Westmead, Australia. yangw@westgate.wh.usyd.edu.au
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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