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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-10-27
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pubmed:abstractText |
Recruitment of leukocytes during immune responses requires the coordinate expression of adhesion molecules in concert with chemokines and their receptors. The Duffy antigen receptor for chemokines (DARC) binds multiple chemokines and is expressed on postcapillary venules in the normal kidney. The chemokine receptor CCR5, which shares the ligand regulated upon activation, normal T-cell expressed and secreted (RANTES) with DARC, is expressed by infiltrating T cells in the renal interstitium. As DARC might be involved in the attraction of CCR5-positive cells, we studied the distribution of DARC and CCR5 in two forms of cell-mediated renal injury: renal allograft rejection and crescentic glomerulonephritis (cGN).
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Protozoan,
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL5,
http://linkedlifedata.com/resource/pubmed/chemical/DARC protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Duffy Blood-Group System,
http://linkedlifedata.com/resource/pubmed/chemical/Duffy antigen binding protein...,
http://linkedlifedata.com/resource/pubmed/chemical/Protozoan Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, CCR5,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1546-56
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:11012889-Acute Disease,
pubmed-meshheading:11012889-Antibodies, Monoclonal,
pubmed-meshheading:11012889-Antigens, Protozoan,
pubmed-meshheading:11012889-Biopsy,
pubmed-meshheading:11012889-Carrier Proteins,
pubmed-meshheading:11012889-Cell Adhesion,
pubmed-meshheading:11012889-Chemokine CCL5,
pubmed-meshheading:11012889-Duffy Blood-Group System,
pubmed-meshheading:11012889-Glomerulonephritis,
pubmed-meshheading:11012889-Graft Rejection,
pubmed-meshheading:11012889-Humans,
pubmed-meshheading:11012889-Immunity, Cellular,
pubmed-meshheading:11012889-Kidney Glomerulus,
pubmed-meshheading:11012889-Kidney Transplantation,
pubmed-meshheading:11012889-Leukocytes,
pubmed-meshheading:11012889-Palatine Tonsil,
pubmed-meshheading:11012889-Protozoan Proteins,
pubmed-meshheading:11012889-Receptors, CCR5,
pubmed-meshheading:11012889-Receptors, Cell Surface,
pubmed-meshheading:11012889-Transplantation, Homologous,
pubmed-meshheading:11012889-Up-Regulation,
pubmed-meshheading:11012889-Venules
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pubmed:year |
2000
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pubmed:articleTitle |
The Duffy antigen receptor for chemokines is up-regulated during acute renal transplant rejection and crescentic glomerulonephritis.
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pubmed:affiliation |
Medizinische Poliklinik, Klinikum der Universität, Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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