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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2000-11-16
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pubmed:abstractText |
Proton pump inhibitors including omeprazole and lansoprazole inhibit gastric acid secretion by selectively and non-competitively inactivating the H+, K+ ATPase molecules of the parietal cell, but possibly only those that are actively secreting acid. This might imply that stimulation of acid secretion by a meal is necessary for optimal inhibition of gastric secretion.
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pubmed:language |
eng
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pubmed:journal |
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|
pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0269-2813
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
14
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
1267-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11012470-2-Pyridinylmethylsulfinylbenzimidazoles,
pubmed-meshheading:11012470-Adult,
pubmed-meshheading:11012470-Anti-Ulcer Agents,
pubmed-meshheading:11012470-Cross-Over Studies,
pubmed-meshheading:11012470-Enzyme Inhibitors,
pubmed-meshheading:11012470-Female,
pubmed-meshheading:11012470-Food-Drug Interactions,
pubmed-meshheading:11012470-Gastric Acid,
pubmed-meshheading:11012470-Gastric Acidity Determination,
pubmed-meshheading:11012470-Humans,
pubmed-meshheading:11012470-Male,
pubmed-meshheading:11012470-Manometry,
pubmed-meshheading:11012470-Middle Aged,
pubmed-meshheading:11012470-Omeprazole,
pubmed-meshheading:11012470-Proton Pumps
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|
pubmed:year |
2000
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|
pubmed:articleTitle |
Proton pump inhibitors: better acid suppression when taken before a meal than without a meal.
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|
pubmed:affiliation |
Oesophageal Research Laboratory, Department of Medicine, The Graduate Hospital, Philadelphia, Pennsylvania, USA.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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