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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
19
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pubmed:dateCreated |
2001-1-3
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pubmed:abstractText |
New analogues of the venerable antimalarial drug primaquine have been synthesized and bioassayed in vivo against Pneumocystis carinii, a life-threatening infection common among immunosuppressed patients. Two of these new compounds are significantly more active than primaquine itself, and provide new information for future drug design and development in this area.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:BoylanC JCJ,
pubmed-author:ByrdJ CJC,
pubmed-author:CurrentW LWL,
pubmed-author:EdwardsC BCB,
pubmed-author:FullerD ADA,
pubmed-author:GoodwinT ETE,
pubmed-author:GreenJ LJL,
pubmed-author:LaroccaC DCD,
pubmed-author:RaneyK DKD,
pubmed-author:RossA SAS,
pubmed-author:TuckerW AWA
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pubmed:issnType |
Print
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pubmed:day |
2
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2205-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:11012030-Animals,
pubmed-meshheading:11012030-Antifungal Agents,
pubmed-meshheading:11012030-Dose-Response Relationship, Drug,
pubmed-meshheading:11012030-Drug Design,
pubmed-meshheading:11012030-Female,
pubmed-meshheading:11012030-Humans,
pubmed-meshheading:11012030-Molecular Structure,
pubmed-meshheading:11012030-Pneumocystis,
pubmed-meshheading:11012030-Pneumocystis Infections,
pubmed-meshheading:11012030-Primaquine,
pubmed-meshheading:11012030-Rats,
pubmed-meshheading:11012030-Structure-Activity Relationship
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pubmed:year |
2000
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pubmed:articleTitle |
Enhanced pneumocystis carinii activity of new primaquine analogues.
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pubmed:affiliation |
Department of Chemistry, Hendrix College, Conway, AR 72032, USA. goodwin@hendrix.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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