Source:http://linkedlifedata.com/resource/pubmed/id/11006956
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
13
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pubmed:dateCreated |
2000-12-28
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pubmed:abstractText |
We examined whether there was any difference in the value, and temporal evolution, of the apparent diffusion tensor trace (ADC) in acute and subacute grey and white matter lesions. Thirty-seven patients underwent diffusion imaging once (up to 3 days), 15 patients were scanned twice (up to 7 days), and seven patients were scanned three times (up to 14 days) after stroke. Values of the ratio of ischaemic to contralateral ADC (ADCr) were reduced on average by 30% (p<0.001) in the whole hyperintense region up to 7 days post-ictus. No difference was seen between ADCr values of grey and white matter in individual subjects within the patient groups scanned up to 7 days. However, in the subgroup of patients scanned beyond 7 days, ADCr for grey matter rose significantly (p=0.02) from ADCr approximately 0.7 (< 7 days) to 0.95 (> or = 10 days). This increase did not occur in white matter whose ADCr remained fairly constant (ADCr approximately 0.7) over the time course of the study.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0959-4965
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2867-74
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:11006956-Acute Disease,
pubmed-meshheading:11006956-Aged,
pubmed-meshheading:11006956-Body Water,
pubmed-meshheading:11006956-Brain Ischemia,
pubmed-meshheading:11006956-Cerebral Cortex,
pubmed-meshheading:11006956-Diffusion,
pubmed-meshheading:11006956-Disease Progression,
pubmed-meshheading:11006956-Female,
pubmed-meshheading:11006956-Humans,
pubmed-meshheading:11006956-Magnetic Resonance Imaging,
pubmed-meshheading:11006956-Male,
pubmed-meshheading:11006956-Middle Aged,
pubmed-meshheading:11006956-Nerve Fibers, Myelinated,
pubmed-meshheading:11006956-Neurons,
pubmed-meshheading:11006956-Stroke,
pubmed-meshheading:11006956-Time Factors
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pubmed:year |
2000
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pubmed:articleTitle |
A study of the apparent diffusion coefficient of grey and white matter in human ischaemic stroke.
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pubmed:affiliation |
Department of Medical and Radiological Sciences (Medical Physics), University of Edinburgh, Western General Hospital.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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