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rdf:type |
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lifeskim:mentions |
|
|
pubmed:issue |
4
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pubmed:dateCreated |
2001-2-2
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pubmed:abstractText |
The term for re-entrainment to a new light-dark cycle in streptozotocin (STZ)-induced diabetic rats was significantly longer than that in control rats. In STZ-induced diabetic rats, the same level of phase delay in the suprachiasmatic nucleus neuronal firing rhythm was observed in control rats after glutamate application. Therefore, 5-HT function in the hypothalamus is thought to be decreased in STZ-induced diabetic rats. These results suggest that postsynaptic neuronal function is still maintained in the suprachiasmatic nucleus of STZ-induced diabetic rats. Therefore, 5-HT mechanisms may play an important role in the maintenance of this function.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0021-5198
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
83
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
355-8
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:11001184-5-Hydroxytryptophan,
pubmed-meshheading:11001184-Animals,
pubmed-meshheading:11001184-Brain,
pubmed-meshheading:11001184-Circadian Rhythm,
pubmed-meshheading:11001184-Diabetes Mellitus, Experimental,
pubmed-meshheading:11001184-Glutamic Acid,
pubmed-meshheading:11001184-Hydroxyindoleacetic Acid,
pubmed-meshheading:11001184-Male,
pubmed-meshheading:11001184-Motor Activity,
pubmed-meshheading:11001184-Rats,
pubmed-meshheading:11001184-Rats, Wistar,
pubmed-meshheading:11001184-Serotonin,
pubmed-meshheading:11001184-Streptozocin,
pubmed-meshheading:11001184-Suprachiasmatic Nucleus
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pubmed:year |
2000
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|
pubmed:articleTitle |
Entrainment function in the suprachiasmatic nucleus of streptozotocin-induced diabetic rats.
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|
pubmed:affiliation |
Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article
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