Linked Life Data

10996505

Source:http://linkedlifedata.com/resource/pubmed/id/10996505

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-10-19
pubmed:abstractText
Circadian rhythms are endogenously-mediated 24 h cycles of behavioral or physiological activity. The interactions among the mammalian circadian clock, acute seizures, and chronic epilepsy are not well-characterized. Evidence suggests that seizures are susceptible to circadian modulation, and that this modulation varies with epilepsy syndrome and location of seizure foci. The circadian timing system and secondary circadian cycles of hormone secretion, sleep and wakefulness, and recurrent environmental factors are discussed as potential systems that effect spontaneous seizure recurrence. Experimental designs should take into account time-of-day effects on seizure threshold and occurrence. Further work is required to determine what mechanisms account for daily variation in seizure susceptibility.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0920-1211
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
43-55
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Circadian rhythms: interactions with seizures and epilepsy.
pubmed:affiliation
NSF Center for Biological Timing, Department of Neurology, University of Virginia, Box 394, HSC, Charlottesville, VA 22908, USA. quigg@virginia.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't