Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2000-11-16
pubmed:databankReference
pubmed:abstractText
Ropp 120 (restrictedly overexpressed proliferation-associated protein) is a cytoplasmic protein of 120 kDa that is significantly overexpressed in mitotic cells. Protein sequencing of the immunoaffinity purified 120-kDa protein showed it to be an as yet unknown protein. DNA sequencing revealed a cDNA sequence of 3419 bases, which includes the complete coding region of ropp120 of 2943 bases (981 amino acids). Analysis of the deduced amino acid sequence showed that ropp 120 contains four WD repeats and a well-conserved consensus sequence of serine proteases. The gene encoding ropp120 (HGMW-approved gene symbol C2orf2) was assigned to chromosome 2p21-p22 by means of radiation hybrid and fluorescence in situ hybridization mapping.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0888-7543
pubmed:author
pubmed:copyrightInfo
Copyright 2000 Academic Press.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
348-50
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:10995578-Amino Acid Sequence, pubmed-meshheading:10995578-Animals, pubmed-meshheading:10995578-Base Sequence, pubmed-meshheading:10995578-Cell Cycle, pubmed-meshheading:10995578-Cell Cycle Proteins, pubmed-meshheading:10995578-Chromosome Mapping, pubmed-meshheading:10995578-Cloning, Molecular, pubmed-meshheading:10995578-Cytoplasm, pubmed-meshheading:10995578-Humans, pubmed-meshheading:10995578-In Situ Hybridization, Fluorescence, pubmed-meshheading:10995578-L Cells (Cell Line), pubmed-meshheading:10995578-Mice, pubmed-meshheading:10995578-Microtubule-Associated Proteins, pubmed-meshheading:10995578-Mitosis, pubmed-meshheading:10995578-Molecular Sequence Data, pubmed-meshheading:10995578-Recombinant Proteins, pubmed-meshheading:10995578-Repetitive Sequences, Amino Acid, pubmed-meshheading:10995578-Sequence Tagged Sites, pubmed-meshheading:10995578-Serine Endopeptidases
pubmed:year
2000
pubmed:articleTitle
Cloning and localization of C2orf2(ropp120), a previously unknown WD repeat protein.
pubmed:affiliation
Department of Hematopathology and Lymph Node Registry, German Association of Pathologists, University of Kiel, Michaelisstrasse 11, Kiel, D-24105, Germany. hheidebrecht@path.uni-kiel.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't