Linked Life Data

10994776

Source:http://linkedlifedata.com/resource/pubmed/id/10994776

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-12-26
pubmed:abstractText
Skin surface morphology has long been recognized as reflecting skin pathology. In the present study, we evaluated skin surface morphology using hairless mice under contrasting conditions of humidity. The skin surface microrelief was recorded with opaque quick-drying silicone rubber, and examined under a microscope. A binary image was produced by density slicing. Within 3 days of exposure to dry conditions, skin roughness was significantly increased. The skin roughness was partially mitigated by topical application of an aqueous solution of glycerol or hydration by immersion in water. A significant correlation between skin roughness and stratum corneum thickness was also observed. These results suggest that skin surface morphology is associated with both water content and thickness of the stratum corneum.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0340-3696
pubmed:author
pubmed:issnType
Print
pubmed:volume
292
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
412-7
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Water content and thickness of the stratum corneum contribute to skin surface morphology.
pubmed:affiliation
Skin Biology Research Laboratories, Shiseido Research Center, Yokohama, Japan.
pubmed:publicationType
Journal Article