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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2000-12-28
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pubmed:abstractText |
The observation of local 'elementary' Ca2+ release events (Ca2+ sparks) through ryanodine receptor (RyR) channels in the sarcoplasmic reticulum (SR) has changed our understanding of excitation-contraction (EC) coupling in cardiac and smooth muscle. In arterial smooth muscle, Ca2+ sparks have been suggested to oppose myogenic vasoconstriction and to influence vasorelaxation by activating co-localized Ca2+ activated K+ (K(Ca)) channels (STOCs). However, all prior studies on Ca2+ sparks have been performed in non-human tissues.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,2-bis(2-aminophenoxy)ethane...,
http://linkedlifedata.com/resource/pubmed/chemical/Aniline Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Chelating Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Egtazic Acid,
http://linkedlifedata.com/resource/pubmed/chemical/Fluo-3,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Ryanodine,
http://linkedlifedata.com/resource/pubmed/chemical/Ryanodine Receptor Calcium Release...,
http://linkedlifedata.com/resource/pubmed/chemical/Xanthenes
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0263-6352
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1215-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10994752-Aniline Compounds,
pubmed-meshheading:10994752-Biological Transport,
pubmed-meshheading:10994752-Calcium,
pubmed-meshheading:10994752-Chelating Agents,
pubmed-meshheading:10994752-Coronary Vessels,
pubmed-meshheading:10994752-Egtazic Acid,
pubmed-meshheading:10994752-Female,
pubmed-meshheading:10994752-Fluorescent Dyes,
pubmed-meshheading:10994752-Humans,
pubmed-meshheading:10994752-Male,
pubmed-meshheading:10994752-Microscopy, Confocal,
pubmed-meshheading:10994752-Muscle, Smooth, Vascular,
pubmed-meshheading:10994752-Potassium Channels,
pubmed-meshheading:10994752-Ryanodine,
pubmed-meshheading:10994752-Ryanodine Receptor Calcium Release Channel,
pubmed-meshheading:10994752-Sarcoplasmic Reticulum,
pubmed-meshheading:10994752-Vasoconstriction,
pubmed-meshheading:10994752-Vasodilation,
pubmed-meshheading:10994752-Xanthenes
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pubmed:year |
2000
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pubmed:articleTitle |
Calcium sparks in human coronary artery smooth muscle cells resolved by confocal imaging.
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pubmed:affiliation |
Franz Volhard Clinic at the Max Delbrück Center for Molecular Medicine, Charité University Hospitals, Humboldt University Berlin, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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