|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0010640,
umls-concept:C0010642,
umls-concept:C0019878,
umls-concept:C0023890,
umls-concept:C0030705,
umls-concept:C0221099,
umls-concept:C0229671,
umls-concept:C0441889,
umls-concept:C0442805,
umls-concept:C0686907,
umls-concept:C1156853
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|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2001-1-11
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|
pubmed:abstractText |
It has been suggested that the major metabolic block in the methionine catabolic pathway in cirrhotics exists at the level of the enzyme S-adenosylmethionine synthetase because in previous studies using conventional amino-acid analyzers, no intermediates of transmethylation/transsulfuration were found to accumulate in plasma downstream of S-adenosylmethionine synthesis. We therefore measured serum concentration intermediates of methionine transmethylation/transsulfuration using an improved gas chromatography/mass spectrometry technique.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0036-5521
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
35
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
866-72
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10994627-Adolescent,
pubmed-meshheading:10994627-Adult,
pubmed-meshheading:10994627-Aged,
pubmed-meshheading:10994627-Analysis of Variance,
pubmed-meshheading:10994627-Biological Markers,
pubmed-meshheading:10994627-Chromatography, Gas,
pubmed-meshheading:10994627-Cystathionine,
pubmed-meshheading:10994627-Cystathionine gamma-Lyase,
pubmed-meshheading:10994627-Female,
pubmed-meshheading:10994627-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:10994627-Homocysteine,
pubmed-meshheading:10994627-Humans,
pubmed-meshheading:10994627-Liver Cirrhosis,
pubmed-meshheading:10994627-Male,
pubmed-meshheading:10994627-Middle Aged,
pubmed-meshheading:10994627-Probability,
pubmed-meshheading:10994627-Reference Values,
pubmed-meshheading:10994627-Sensitivity and Specificity,
pubmed-meshheading:10994627-Severity of Illness Index,
pubmed-meshheading:10994627-Statistics, Nonparametric
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|
pubmed:year |
2000
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pubmed:articleTitle |
Is the increase in serum cystathionine levels in patients with liver cirrhosis a consequence of impaired homocysteine transsulfuration at the level of gamma-cystathionase?
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pubmed:affiliation |
Dept. of Internal Medicine I, University of Bonn, Germany.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Controlled Clinical Trial
|
