Source:http://linkedlifedata.com/resource/pubmed/id/10992834
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2000-9-21
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pubmed:abstractText |
We compared the onset of neuromuscular block with succinylcholine (1 mg kg-1) and two doses of rocuronium (0.6 and 0.9 mg kg-1) at the adductor pollicis muscle using electromyography (EMG) and acceleromyography (AMG), and at the adductor laryngeal muscles with a new electromyographic method using a disposable surface electrode attached to the cuff of a tracheal tube. At the larynx, the mean (+/- SD) time to 90% block and the onset time of succinylcholine (38 +/- 15 and 47 +/- 19 s, respectively) were significantly shorter (P < 0.01) than for rocuronium 0.6 mg kg-1 (92 +/- 42 and 106 +/- 38 s) and rocuronium 0.9 mg kg-1 (52 +/- 31 and 64 +/- 30 s). We found that, with comparable degrees of neuromuscular block, the onset time of succinylcholine at the adductor pollicis was significantly shorter (P < 0.01) than for rocuronium 0.6 mg kg-1 and 0.9 mg kg-1 (EMG, 80 +/- 39 vs 145 +/- 48 s and 99 +/- 31 s; AMG, 90 +/- 39 vs 124 +/- 53 s and 106 +/- 38 s). Clinical duration at the adductor pollicis (AMG) was significantly longer (P < 0.01) for both rocuronium groups than for succinylcholine (T4:T1 = 0.7, 54 +/- 18 and 77 +/- 21 vs 8 +/- 6 min). The surface laryngeal electrode proved non-invasive, easy to use and reliable in measuring onset of the neuromuscular block at the larynx.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Androstanols,
http://linkedlifedata.com/resource/pubmed/chemical/Neuromuscular Depolarizing Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Neuromuscular Nondepolarizing Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Succinylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/rocuronium
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0007-0912
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
85
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
251-5
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10992834-Adult,
pubmed-meshheading:10992834-Aged,
pubmed-meshheading:10992834-Aged, 80 and over,
pubmed-meshheading:10992834-Analysis of Variance,
pubmed-meshheading:10992834-Androstanols,
pubmed-meshheading:10992834-Electromyography,
pubmed-meshheading:10992834-Female,
pubmed-meshheading:10992834-Humans,
pubmed-meshheading:10992834-Laryngeal Muscles,
pubmed-meshheading:10992834-Male,
pubmed-meshheading:10992834-Middle Aged,
pubmed-meshheading:10992834-Monitoring, Intraoperative,
pubmed-meshheading:10992834-Muscle, Skeletal,
pubmed-meshheading:10992834-Neuromuscular Blockade,
pubmed-meshheading:10992834-Neuromuscular Depolarizing Agents,
pubmed-meshheading:10992834-Neuromuscular Nondepolarizing Agents,
pubmed-meshheading:10992834-Succinylcholine
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pubmed:year |
2000
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pubmed:articleTitle |
Comparison of succinylcholine with two doses of rocuronium using a new method of monitoring neuromuscular block at the laryngeal muscles by surface laryngeal electromyography.
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pubmed:affiliation |
Department of Anaesthesiology, University of Erlangen, Nuremberg, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
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