rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2000-11-3
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pubmed:abstractText |
We compared the ability of Salmonella enterica serovar Typhimurium SL1344 aroA aroD (BRD509) and aroA htrA (BRD807) mutants to act as live vectors for delivery of fragment C of tetanus toxin (FrgC). FrgC was expressed in these strains from either pTETnir15 or pTEThtrA1. BRD509FrgC(+) strains elicited approximately 2-log-higher serum anti-FrgC antibody titers than BRD807FrgC(+) strains. All mice immunized with BRD807pTEThtrA1, BRD509pTEThtrA1, and BRD509pTETnir15 (but not BRD807pTETnir15) were protected against tetanus.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-10084987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-10417142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-10603389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-10678926,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-1398911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-1584006,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-1730487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-8717403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-9009296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-9413986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-9453634,
http://linkedlifedata.com/resource/pubmed/commentcorrection/10992518-9632569
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3-Phosphoshikimate...,
http://linkedlifedata.com/resource/pubmed/chemical/3-dehydroquinate dehydratase,
http://linkedlifedata.com/resource/pubmed/chemical/Alkyl and Aryl Transferases,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Vaccines,
http://linkedlifedata.com/resource/pubmed/chemical/DegP protease,
http://linkedlifedata.com/resource/pubmed/chemical/Heat-Shock Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hydro-Lyases,
http://linkedlifedata.com/resource/pubmed/chemical/Peptide Fragments,
http://linkedlifedata.com/resource/pubmed/chemical/Periplasmic Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Tetanus Toxin,
http://linkedlifedata.com/resource/pubmed/chemical/Vaccines, Attenuated,
http://linkedlifedata.com/resource/pubmed/chemical/tetanus toxin fragment C
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0019-9567
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
6041-3
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:10992518-3-Phosphoshikimate 1-Carboxyvinyltransferase,
pubmed-meshheading:10992518-Alkyl and Aryl Transferases,
pubmed-meshheading:10992518-Animals,
pubmed-meshheading:10992518-Antibodies, Bacterial,
pubmed-meshheading:10992518-Bacterial Vaccines,
pubmed-meshheading:10992518-Genetic Vectors,
pubmed-meshheading:10992518-Heat-Shock Proteins,
pubmed-meshheading:10992518-Hydro-Lyases,
pubmed-meshheading:10992518-Immunization,
pubmed-meshheading:10992518-Mice,
pubmed-meshheading:10992518-Mutation,
pubmed-meshheading:10992518-Peptide Fragments,
pubmed-meshheading:10992518-Periplasmic Proteins,
pubmed-meshheading:10992518-Salmonella Infections, Animal,
pubmed-meshheading:10992518-Salmonella typhimurium,
pubmed-meshheading:10992518-Serine Endopeptidases,
pubmed-meshheading:10992518-Tetanus,
pubmed-meshheading:10992518-Tetanus Toxin,
pubmed-meshheading:10992518-Vaccines, Attenuated
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pubmed:year |
2000
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pubmed:articleTitle |
Comparison of abilities of Salmonella enterica serovar typhimurium aroA aroD and aroA htrA mutants to act as live vectors.
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pubmed:affiliation |
Department of Veterinary Pathology, Glasgow University Veterinary School, Glasgow G61 1QH, United Kingdom. M.Roberts@vet.gla.ac.uk
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pubmed:publicationType |
Journal Article,
Comparative Study
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