|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002482,
umls-concept:C0005821,
umls-concept:C0016011,
umls-concept:C0029266,
umls-concept:C0035253,
umls-concept:C0205198,
umls-concept:C0242808,
umls-concept:C0243076,
umls-concept:C0597357,
umls-concept:C1510827,
umls-concept:C1521761,
umls-concept:C1879547
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|
pubmed:issue |
17
|
|
pubmed:dateCreated |
2001-1-4
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|
pubmed:abstractText |
Compound affinity for activated and resting GPIIb/IIIa receptors may differ, and comparison of those differences determines selectivity. Structural features that influence selectivity are discussed.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
pubmed-author:AskewB CBC,
pubmed-author:BednarBB,
pubmed-author:BednarR ARA,
pubmed-author:BrashearKK,
pubmed-author:BreslinM JMJ,
pubmed-author:DugganM EME,
pubmed-author:EgbertsonM SMS,
pubmed-author:FisherT ETE,
pubmed-author:GouldR JRJ,
pubmed-author:HalczenkoWW,
pubmed-author:HartmanG DGD,
pubmed-author:HutchinsonJ HJH,
pubmed-author:IhleNN,
pubmed-author:PrughJ DJD,
pubmed-author:WaiJ SJS
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|
pubmed:issnType |
Print
|
|
pubmed:day |
4
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1943-8
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Nonpeptide GPIIB/IIIA receptor antagonists. Part 21: C-6 flexibility and amide bond orientation are important factors in determining the affinity of compounds for activated or resting platelet receptors.
|
|
pubmed:affiliation |
Merck Research Laboratories, Department of Medicinal Chemistry, West Point, PA 19486, USA. melissa_egbertson@merck.com
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pubmed:publicationType |
Journal Article
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