Linked Life Data

10985573

Source:http://linkedlifedata.com/resource/pubmed/id/10985573

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2000-12-11
pubmed:abstractText
A reversed-phase HPLC method was developed for quantitative analysis of malagashanine in rat plasma and urine. Malagashanine and internal standard were extracted from alkalinized rat plasma. Urine analysis was performed by direct injection onto the HPLC system. Acetonitrile-aqueous 25 mM sodium acetate solution at pH 6.25 (45:55, v/v) was used as the mobile phase. The eluate was monitored by using UV detection at 250 nm. The assay was linear within the concentration range of 10-1000 ng/ml. Both intra- and inter-day accuracy and precision were within acceptable limits. The method was applied to study the pharmacokinetics of malagashanine in rats.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
1387-2273
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
744
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
121-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
High-performance liquid chromatographic assay of malagashanine in rat plasma and urine and its pharmacokinetic application.
pubmed:affiliation
Laboratoire de Pharmacologie Générale et de Pharmacocinétique, Faculté des Sciences, Université d'Antananarivo, Madagascar.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't