|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
9
|
|
pubmed:dateCreated |
2001-1-3
|
|
pubmed:abstractText |
Early-onset periodontal diseases (EOP) are a group of inflammatory disorders characterised by a rapid rate of periodontal tissue destruction, in young individuals who are otherwise healthy. There is now substantial evidence to suggest that genetic factors play a rôle in the pathogenesis of EOP but the precise nature of these factors remains unclear. Polymorphisms in cytokine genes which may underpin inter-individual differences in cytokine synthesis and secretion have been associated with other diseases which have an inflammatory pathogenesis, including chronic adult periodontal disease (CAPD).
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
D
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
0303-6979
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
27
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
682-9
|
|
pubmed:dateRevised |
2006-11-15
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|
pubmed:meshHeading |
pubmed-meshheading:10983602-Adolescent,
pubmed-meshheading:10983602-Adult,
pubmed-meshheading:10983602-Alleles,
pubmed-meshheading:10983602-Base Sequence,
pubmed-meshheading:10983602-DNA,
pubmed-meshheading:10983602-DNA Primers,
pubmed-meshheading:10983602-Female,
pubmed-meshheading:10983602-Genotype,
pubmed-meshheading:10983602-Humans,
pubmed-meshheading:10983602-Interleukin 1 Receptor Antagonist Protein,
pubmed-meshheading:10983602-Interleukin-1,
pubmed-meshheading:10983602-Male,
pubmed-meshheading:10983602-Middle Aged,
pubmed-meshheading:10983602-Molecular Sequence Data,
pubmed-meshheading:10983602-Periodontitis,
pubmed-meshheading:10983602-Polymerase Chain Reaction,
pubmed-meshheading:10983602-Polymorphism, Genetic,
pubmed-meshheading:10983602-Receptors, Interleukin-1,
pubmed-meshheading:10983602-Sialoglycoproteins
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|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Association of interleukin-1 gene polymorphisms with early-onset periodontitis.
|
|
pubmed:affiliation |
Department of Oral Biology, The Dental School, University of Newcastle upon Tyne, UK.
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|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|
