rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3
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pubmed:dateCreated |
2000-9-29
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pubmed:abstractText |
There is increasing evidence that trefoil factor family 1 (TFF1) is a stabilizer of the mucous gel overlying the gastrointestinal mucosa that provides a physical barrier against various noxious agents. TFF1 knockout mice developed multiple gastric adenomas and carcinomas, suggesting that TFF1 is a gastric-specific tumor-suppressor gene.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:KimH SHS,
pubmed-author:KimS YSY,
pubmed-author:KimY SYS,
pubmed-author:LeeH KHK,
pubmed-author:LeeJ HJH,
pubmed-author:LeeJ YJY,
pubmed-author:LeeS HSH,
pubmed-author:ParkJ YJY,
pubmed-author:ParkW SWS,
pubmed-author:QuS FSF,
pubmed-author:ShinM SMS,
pubmed-author:YooN JNJ
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pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
691-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10982763-Adult,
pubmed-meshheading:10982763-Aged,
pubmed-meshheading:10982763-Amino Acid Sequence,
pubmed-meshheading:10982763-Base Sequence,
pubmed-meshheading:10982763-DNA Mutational Analysis,
pubmed-meshheading:10982763-Female,
pubmed-meshheading:10982763-Gastric Mucosa,
pubmed-meshheading:10982763-Growth Substances,
pubmed-meshheading:10982763-Humans,
pubmed-meshheading:10982763-Immunohistochemistry,
pubmed-meshheading:10982763-Loss of Heterozygosity,
pubmed-meshheading:10982763-Male,
pubmed-meshheading:10982763-Middle Aged,
pubmed-meshheading:10982763-Molecular Sequence Data,
pubmed-meshheading:10982763-Mucins,
pubmed-meshheading:10982763-Multigene Family,
pubmed-meshheading:10982763-Muscle Proteins,
pubmed-meshheading:10982763-Mutation,
pubmed-meshheading:10982763-Neuropeptides,
pubmed-meshheading:10982763-Peptides,
pubmed-meshheading:10982763-Reference Values,
pubmed-meshheading:10982763-Stomach Neoplasms
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pubmed:year |
2000
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pubmed:articleTitle |
Somatic mutations of the trefoil factor family 1 gene in gastric cancer.
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pubmed:affiliation |
Department of Pathology and Genetic Oncology Laboratory, College of Medicine, The Catholic University of Korea, Seoul, Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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