Source:http://linkedlifedata.com/resource/pubmed/id/10978721
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2000-11-16
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pubmed:abstractText |
Acetylcholine is important to hippocampal function, including the processes of learning and memory. Patients with schizophrenia show impaired learning and memory and hippocampal dysfunction. Thus, acetylcholinergic systems may be primarily or secondarily disrupted in the hippocampal formation of schizophrenic patients. The present study tested the hypothesis that [(3)H]pirenzepine-labeled muscarinic cholinergic receptor levels are altered in the hippocampal formation of patients with schizophrenia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0006-3223
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
381-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10978721-Adult,
pubmed-meshheading:10978721-Aged,
pubmed-meshheading:10978721-Autoradiography,
pubmed-meshheading:10978721-Female,
pubmed-meshheading:10978721-Hippocampus,
pubmed-meshheading:10978721-Humans,
pubmed-meshheading:10978721-Male,
pubmed-meshheading:10978721-Middle Aged,
pubmed-meshheading:10978721-Muscarinic Antagonists,
pubmed-meshheading:10978721-Pirenzepine,
pubmed-meshheading:10978721-Receptors, Muscarinic,
pubmed-meshheading:10978721-Schizophrenia
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pubmed:year |
2000
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pubmed:articleTitle |
Decreased muscarinic receptor binding in subjects with schizophrenia: a study of the human hippocampal formation.
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pubmed:affiliation |
The Rebecca L. Cooper Research Laboratories, Division of Molecular Schizophrenia, The Mental Health Research Institute, Parkville, Victoria, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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