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pubmed-article:10972484pubmed:abstractTextCryptophycins are a family of antitubulin antitumor agents. A synthetic cryptophycin derivative (LY355703, CRYPTO 52) is in early clinical evaluation. The effect of infusion time on the antitumor activity of four cryptophycins was assessed in rats bearing the 13762 mammary carcinoma and combination treatment regimens were assessed in nude mice bearing human tumor xenografts.lld:pubmed
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pubmed-article:10972484pubmed:articleTitleAntitumor activity of cryptophycins: effect of infusion time and combination studies.lld:pubmed
pubmed-article:10972484pubmed:affiliationLilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA.lld:pubmed
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