rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
2
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pubmed:dateCreated |
2000-9-25
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pubmed:abstractText |
Cryptophycins are a family of antitubulin antitumor agents. A synthetic cryptophycin derivative (LY355703, CRYPTO 52) is in early clinical evaluation. The effect of infusion time on the antitumor activity of four cryptophycins was assessed in rats bearing the 13762 mammary carcinoma and combination treatment regimens were assessed in nude mice bearing human tumor xenografts.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:issn |
0344-5704
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
142-9
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pubmed:dateRevised |
2006-4-24
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pubmed:meshHeading |
pubmed-meshheading:10972484-Animals,
pubmed-meshheading:10972484-Antibiotics, Antineoplastic,
pubmed-meshheading:10972484-Antineoplastic Agents,
pubmed-meshheading:10972484-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:10972484-Carcinoma,
pubmed-meshheading:10972484-Depsipeptides,
pubmed-meshheading:10972484-Female,
pubmed-meshheading:10972484-Humans,
pubmed-meshheading:10972484-Infusions, Intravenous,
pubmed-meshheading:10972484-Lactams,
pubmed-meshheading:10972484-Lactones,
pubmed-meshheading:10972484-Lung Neoplasms,
pubmed-meshheading:10972484-Male,
pubmed-meshheading:10972484-Mammary Neoplasms, Experimental,
pubmed-meshheading:10972484-Mice,
pubmed-meshheading:10972484-Mice, Nude,
pubmed-meshheading:10972484-Peptides, Cyclic,
pubmed-meshheading:10972484-Rats,
pubmed-meshheading:10972484-Rats, Inbred F344,
pubmed-meshheading:10972484-Transplantation, Heterologous
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pubmed:year |
2000
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pubmed:articleTitle |
Antitumor activity of cryptophycins: effect of infusion time and combination studies.
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pubmed:affiliation |
Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, IN 46285, USA.
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pubmed:publicationType |
Journal Article
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