Linked Life Data

10971963

Source:http://linkedlifedata.com/resource/pubmed/id/10971963

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2000-10-12
pubmed:abstractText
Efficiency of various protocols of specific immunoglobulin treatment was evaluated in golden hamsters inoculated with two Far Eastern tick-borne encephalitis (TBE) strains. After a low therapeutic dose (0.1 ml) of immunoglobulin, corresponding to total dose (60 ml) per course, all parameters (survival, immunogenicity, pathomorphology of the brain) deteriorated in animals infected with both strains. A higher dose (0.2 ml) corresponding to total dose of 120 ml notably improved all the studied parameters. The efficiency of specific immunoglobulin depends on the clinical and pathogenetic characteristics of TBE, determined by the properties of TBE strains. The results validate therapy and prevention of TBE by high-titer immunoglobulin in adequate total dose, monitored by blood analyses for TBE antigen and evaluations of the time course of IgM antibodies.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0507-4088
pubmed:author
pubmed:issnType
Print
pubmed:volume
45
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
28-33
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
[Experimental tick-borne encephalitis in golden hamsters treated with specific immunotherapy].
pubmed:publicationType
Journal Article, English Abstract