Linked Life Data

10971551

Source:http://linkedlifedata.com/resource/pubmed/id/10971551

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-10-19
pubmed:abstractText
The partial CO2 rebreathing technique has been shown to be a reliable non-invasive method for measurement of pulmonary capillary blood flow (Qc), but experience with this technique has been limited to controlled mechanical ventilation. In this study, we evaluated this technique during spontaneous and oriented ventilation in nine subjects without known cardiopulmonary disease. Subjects underwent 10 consecutive (Qc) measurements with both spontaneous and oriented ventilation. Breath-by-breath gas exchange was measured and (Qc) was calculated from changes in CO2 elimination and PETCO2, which were achieved by sudden increase of the apparatus deadspace (rebreathing period). An exponential curve was fitted to the PETCO2 values in the rebreathing period in order to estimate PETCO2 at equilibrium. We found that mean (Qc) values were not influenced by the ventilation pattern (P=0.51), but that the intra-individual variability with oriented ventilation (median=16.0%) was significantly lower than with spontaneous ventilation (median=31.8%, P=0.039). Accordingly, the curve fitting for rebreathing PETCO2 rise failed in 4.4% of measurements with oriented ventilation vs. 18.9% of measurements with spontaneous ventilation (P=0.039). Our results suggest that the performance of the partial CO2 rebreathing technique is adversely affected by spontaneous ventilation and, consequently, that this method should be reserved for patients with regular respiratory patterns.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0144-5979
pubmed:author
pubmed:issnType
Print
pubmed:volume
20
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
388-98
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Pulmonary capillary blood flow by partial CO2 rebreathing: importance of the regularity of the respiratory pattern.
pubmed:affiliation
Clinic of Anesthesiology and Intensive Care Medicine, University Clinic Carl Gustav Carus, Technical University Dresden, Dresden, Germany.
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't