|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0020155,
umls-concept:C0031849,
umls-concept:C0041657,
umls-concept:C0439825,
umls-concept:C0599946,
umls-concept:C0678587,
umls-concept:C0871261,
umls-concept:C1301882,
umls-concept:C1555029,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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|
pubmed:issue |
3
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|
pubmed:dateCreated |
2000-9-22
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|
pubmed:abstractText |
It is postulated that alteration of central cholinergic transmission plays an important role in the mechanism by which anesthetics produce unconsciousness. The authors investigated the effect of altering central cholinergic transmission, by physostigmine and scopolamine, on unconsciousness produced by propofol.
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
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pubmed:issn |
0003-3022
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
93
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
708-17
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10969304-Adolescent,
pubmed-meshheading:10969304-Adult,
pubmed-meshheading:10969304-Anesthetics, Intravenous,
pubmed-meshheading:10969304-Brain,
pubmed-meshheading:10969304-Cholinesterase Inhibitors,
pubmed-meshheading:10969304-Consciousness,
pubmed-meshheading:10969304-Double-Blind Method,
pubmed-meshheading:10969304-Electroencephalography,
pubmed-meshheading:10969304-Electrooculography,
pubmed-meshheading:10969304-Humans,
pubmed-meshheading:10969304-Male,
pubmed-meshheading:10969304-Physostigmine,
pubmed-meshheading:10969304-Propofol
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|
pubmed:year |
2000
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|
pubmed:articleTitle |
Physostigmine reverses propofol-induced unconsciousness and attenuation of the auditory steady state response and bispectral index in human volunteers.
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pubmed:affiliation |
Department of Anaesthesia, Royal Victoria Hospital, Montreal, Quebec, Canada.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|
