Source:http://linkedlifedata.com/resource/pubmed/id/10969271
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-10-3
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pubmed:abstractText |
To test the hypothesis that kwashiorkor is associated with increased oxidative stress, urinary concentrations of 2 oxidized amino acids, o,o '-dityrosine and ortho -tyrosine, were measured by gas chromatography-mass spectrometry. Children with kwashiorkor, with or without infection, had a 3- to 7-fold increase in urinary o,o '-dityrosine and a 1.5- to 2-fold increase in ortho -tyrosine when compared with well-nourished children. This observation raises the possibility that oxidative damage to proteins and other biologic targets plays a role in the clinical manifestations of kwashiorkor.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
137
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10969271-Child, Preschool,
pubmed-meshheading:10969271-Female,
pubmed-meshheading:10969271-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:10969271-Humans,
pubmed-meshheading:10969271-Infection,
pubmed-meshheading:10969271-Isomerism,
pubmed-meshheading:10969271-Kwashiorkor,
pubmed-meshheading:10969271-Male,
pubmed-meshheading:10969271-Oxidative Stress,
pubmed-meshheading:10969271-Tyrosine
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pubmed:year |
2000
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pubmed:articleTitle |
Increased oxidative stress in kwashiorkor.
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pubmed:affiliation |
Department of Pediatrics, St Louis Children's Hospital, St Louis, Missouri 63110, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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