Linked Life Data

10965573

Source:http://linkedlifedata.com/resource/pubmed/id/10965573

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-10-26
pubmed:abstractText
Within the setting of a reference tertiary hospital such as Hospital La Fe, a retrospective study of major germs responsible for urinary infections and their susceptibility to fluoroquinolones was conducted between 1990-1998 in an attempt to quantify the increased resistance found in both in- and out-patients. The rationale for the study was the clinical evidence of resistance to those antimicrobials. E. coli continues to be the most frequently isolated micro-organism in all types of urinary infections in both intra-hospital (50%) and extra-hospital infections (63%), followed by E. faecalis, P. mirabilis, and Klebsiella. When ward patients are compared to patients in Intensive Care Units (ICUs) a number of differences become apparent as regard to the isolated micro-organisms. Current resistance to fluoroquinolones is about 23% for E. coli, 28% for E. faecalis, 6.5% for P. mirabilis, 5% for Klebsiella spp, 15% for Pseudomonas aeruginosa and 9% for Enterobacter spp. When these results are compared to those seen at the beginning of the '90s a highly significant increase is noted for E. coli (from 3 to 23%), E. faecalis (from 4.5 to 28%) and Pseudomonas aeruginosa (from 4 to 15%) with a much lower increase for the remaining micro-organisms. The reasons behind such an increase are numerous, the major one being the massive use of quinolones both in humans and animals, with variations based on age and geographic region. Generalisation of this major increase would lead to future use of fluoroquinolones based on susceptibility in culture, particularly in serious urinary infections.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0210-4806
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
381-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
[Evolution of microbial resistance to fluoroquinolones at a tertiary hospital].
pubmed:affiliation
Servicio de Urología, Hospital Universitario La Fe, Valencia.
pubmed:publicationType
Journal Article, English Abstract