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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-12-4
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pubmed:abstractText |
The mechanism by which chronic myocardial edema causes cardiac dysfunction is poorly understood. We hypothesized that myocardial edema triggers cardiac fibrosis development resulting in cardiac dysfunction. Since collagen is the most abundant constituent of the interstitial matrix, we examined the effects of edema development on cardiac collagen metabolism.
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pubmed:grant |
|
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
1073-9688
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-80
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:10963632-Animals,
pubmed-meshheading:10963632-Blood Pressure,
pubmed-meshheading:10963632-Body Weight,
pubmed-meshheading:10963632-Collagen,
pubmed-meshheading:10963632-Collagenases,
pubmed-meshheading:10963632-Disease Models, Animal,
pubmed-meshheading:10963632-Edema, Cardiac,
pubmed-meshheading:10963632-Endomyocardial Fibrosis,
pubmed-meshheading:10963632-Heart Ventricles,
pubmed-meshheading:10963632-Male,
pubmed-meshheading:10963632-Muscle, Skeletal,
pubmed-meshheading:10963632-Organ Size,
pubmed-meshheading:10963632-Procollagen-Proline Dioxygenase,
pubmed-meshheading:10963632-Pulmonary Artery,
pubmed-meshheading:10963632-RNA, Messenger,
pubmed-meshheading:10963632-Rats,
pubmed-meshheading:10963632-Rats, Sprague-Dawley,
pubmed-meshheading:10963632-Time Factors,
pubmed-meshheading:10963632-Transforming Growth Factor beta
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pubmed:year |
2000
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pubmed:articleTitle |
Effects of myocardial edema on the development of myocardial interstitial fibrosis.
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pubmed:affiliation |
Center for Microvascular and Lymphatic Studies, Department of Anesthesiology, The University of Texas-Houston Medical School, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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