Source:http://linkedlifedata.com/resource/pubmed/id/10963609
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6797
|
| pubmed:dateCreated |
2000-9-14
|
| pubmed:abstractText |
CD1, a conserved family of major histocompatibility (MHC)-like glycoproteins in mammals, specializes in capturing lipid rather than peptide antigen for presentation to T lymphocytes. The principles and mechanisms of this newly discovered immune strategy differ markedly from those governing classical MHC-peptide presentation. They might be exploited for the design of new lipid-based microbial vaccines and adjuvants.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0028-0836
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
17
|
| pubmed:volume |
406
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
788-92
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:10963609-Animals,
pubmed-meshheading:10963609-Antigens, CD1,
pubmed-meshheading:10963609-Humans,
pubmed-meshheading:10963609-Infection,
pubmed-meshheading:10963609-Killer Cells, Natural,
pubmed-meshheading:10963609-Lipids,
pubmed-meshheading:10963609-T-Lymphocytes,
pubmed-meshheading:10963609-Vaccines
|
| pubmed:year |
2000
|
| pubmed:articleTitle |
CD1-restricted T-cell responses and microbial infection.
|
| pubmed:affiliation |
Department of Molecular Biology, Princeton University, New Jersey 08544, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Review,
Research Support, Non-U.S. Gov't
|