Source:http://linkedlifedata.com/resource/pubmed/id/10963608
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6797
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pubmed:dateCreated |
2000-9-14
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pubmed:abstractText |
The innate immune response is the first line of defence against infectious disease. The principal challenge for the host is to detect the pathogen and mount a rapid defensive response. A group of proteins that comprise the Toll or Toll-like family of receptors perform this role in vertebrate and invertebrate organisms. This reflects a remarkable conservation of function and it is therefore not surprising that studies of the mechanism by which they act has revealed new and important insights into host defence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0028-0836
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
406
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
782-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:10963608-Animals,
pubmed-meshheading:10963608-Bacteria,
pubmed-meshheading:10963608-Drosophila Proteins,
pubmed-meshheading:10963608-Humans,
pubmed-meshheading:10963608-Immunity,
pubmed-meshheading:10963608-Immunity, Innate,
pubmed-meshheading:10963608-Membrane Glycoproteins,
pubmed-meshheading:10963608-Receptors, Cell Surface,
pubmed-meshheading:10963608-Signal Transduction,
pubmed-meshheading:10963608-Toll-Like Receptors
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pubmed:year |
2000
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pubmed:articleTitle |
Toll-like receptors in the induction of the innate immune response.
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pubmed:affiliation |
Department of Immunology, University of Washington, Seattle 98195, USA.
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pubmed:publicationType |
Journal Article,
Review
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