Linked Life Data

10959994

Source:http://linkedlifedata.com/resource/pubmed/id/10959994

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2001-2-2
pubmed:abstractText
We evaluated 132 consecutively implanted cemented titanium alloy stems (Ti6-Al7-Nb, SLS-88) after a mean follow-up of 6.6 years (range 5-7 years). Almost 30% of the stems showed significant osteolysis, mainly in the proximal stem area. The amount of osteolysis correlated significantly to a typical pain pattern: dull, circular, and occurring at rest. Six stems had already been revised, and another 7 stems were loose clinically and radiologically, which resulted in a Kaplan-Meier survivorship of 95% for stem revisions and 88% for stem failures (revisions plus loose stems). We found that smaller stem sizes tend to increase the development of osteolysis and loosening. Two factors seem to play a role in early loosening of cemented titanium alloy stems: i) increased elasticity of titanium, which leads in small stem sizes to micromotion between the stem and cement and to cement breakage, and ii) corrosion of the cemented titanium alloy stem and subsequent osteolysis in the adjacent bone. The combination of both factors (high elasticity plus corrosion) accelerates the degradation of the bone anchorage of the stem and initiates early loosening. We advise against the further use of cemented SLS-88 titanium alloy stems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0883-5403
pubmed:author
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
570-5
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
Osteolysis in cemented titanium alloy hip prosthesis.
pubmed:affiliation
Department of Orthopaedic Surgery, University of Berne, Switzerland.
pubmed:publicationType
Journal Article