|
rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
4
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pubmed:dateCreated |
1975-10-7
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pubmed:abstractText |
By the use of the mutagenic substance hydrazine sulphate it is shown that the currently used single determination method for determining point mutations in host-mediated assays with calculation of mutation frequencies can lead to erroneous results. The microbiological basis for a linear-method is presented in which the population growth of the auxotrophic and substance-induced mutants used int he test can be described mathematically during their logarithmic growth phase with regression lines.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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|
pubmed:issn |
0027-5107
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
205-16
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:1095922-Animals,
pubmed-meshheading:1095922-Genetics, Microbial,
pubmed-meshheading:1095922-Hydrazines,
pubmed-meshheading:1095922-Isoniazid,
pubmed-meshheading:1095922-Male,
pubmed-meshheading:1095922-Methods,
pubmed-meshheading:1095922-Mice,
pubmed-meshheading:1095922-Molecular Biology,
pubmed-meshheading:1095922-Mutagens,
pubmed-meshheading:1095922-Mutation,
pubmed-meshheading:1095922-Probability,
pubmed-meshheading:1095922-Salmonella typhimurium,
pubmed-meshheading:1095922-Serratia marcescens,
pubmed-meshheading:1095922-Time Factors
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|
pubmed:year |
1975
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pubmed:articleTitle |
Testing the mutagenic potency of chemical substances in a linear host-mediated assay. I. Experimental microbiological basis.
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pubmed:publicationType |
Journal Article
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