rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2000-12-4
|
pubmed:abstractText |
We report a method for detection of deep venous thrombosis with a technetium 99m-labeled peptide (DMP 444). The N-methyl-arginine-glycine-aspartic acid sequence on DMP 444 binds the glycoprotein IIb/IIIa receptor on activated platelets (inhibition constant [IC50] for fibrinogen binding = 6 nmol/L).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1071-3581
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
7
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
359-64
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10958278-Aged,
pubmed-meshheading:10958278-Animals,
pubmed-meshheading:10958278-Blood Platelets,
pubmed-meshheading:10958278-Dogs,
pubmed-meshheading:10958278-Female,
pubmed-meshheading:10958278-Fibrinogen,
pubmed-meshheading:10958278-Humans,
pubmed-meshheading:10958278-Leg,
pubmed-meshheading:10958278-Male,
pubmed-meshheading:10958278-Middle Aged,
pubmed-meshheading:10958278-Oligopeptides,
pubmed-meshheading:10958278-Organotechnetium Compounds,
pubmed-meshheading:10958278-Platelet Aggregation,
pubmed-meshheading:10958278-Platelet Glycoprotein GPIIb-IIIa Complex,
pubmed-meshheading:10958278-Radiopharmaceuticals,
pubmed-meshheading:10958278-Technetium Compounds,
pubmed-meshheading:10958278-Venous Thrombosis
|
pubmed:articleTitle |
Detection of deep venous thrombosis by DMP 444, a platelet IIb/IIIa antagonist: a preliminary report.
|
pubmed:affiliation |
Yale University School of Medicine, West Haven VA Medical Center, USA.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|