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PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
2000-12-27
pubmed:abstractText
In chronic Q-wave myocardial infarction, QT dispersion is closely correlated with infarct size, but this correlation has not been evaluated for acute myocardial infarction (AMI). The effects of abnormal fatty acid metabolism on QT dispersion were examined in 123 patients with AMI who underwent resting iodine-123-15-iodophenyl 3-methyl pentadecanoic acid (BMIPP)/thallium-201(201Tl) myocardial single photon emission computed tomography (SPECT) and electrocardiographic analysis in the subacute phase. The relationship between BMIPP and 201Tl was defined as match when the total defect score for BMIPP was equal to or smaller than that for 201Tl, and as mismatch when the total defect score for BMIPP was larger than that for 201Tl. Twenty-six patients (21%) demonstrated BMIPP-201Tl match and 97 (79%) demonstrated mismatch. Infarct size was closely correlated with QT dispersion (r=0.67, p<0.001) in patients with BMIPP-201Tl match, but weakly correlated (r=0.30, p<0.005) in patients with BMIPP-201Tl mismatch. For small infarctions, QT dispersion was significantly larger in patients with BMIPP-201Tl mismatch than in those with BMIPP-201Tl match (62+/-24 ms vs 41+/-18 ms, p=0.03), but did not differ between the 2 groups for large infarctions. This study shows that QT dispersion is influenced by infarct size and by the presence of metabolically ischemic but viable myocardium in patients with AMI.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0047-1828
pubmed:author
pubmed:issnType
Print
pubmed:volume
64
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
572-8
pubmed:dateRevised
2006-5-6
pubmed:meshHeading
pubmed-meshheading:10952152-Adult, pubmed-meshheading:10952152-Aged, pubmed-meshheading:10952152-Aged, 80 and over, pubmed-meshheading:10952152-Cell Survival, pubmed-meshheading:10952152-Electrocardiography, pubmed-meshheading:10952152-Fatty Acids, pubmed-meshheading:10952152-Female, pubmed-meshheading:10952152-Heart Function Tests, pubmed-meshheading:10952152-Humans, pubmed-meshheading:10952152-Iodine Radioisotopes, pubmed-meshheading:10952152-Iodobenzenes, pubmed-meshheading:10952152-Male, pubmed-meshheading:10952152-Middle Aged, pubmed-meshheading:10952152-Myocardial Infarction, pubmed-meshheading:10952152-Myocardial Ischemia, pubmed-meshheading:10952152-Retrospective Studies, pubmed-meshheading:10952152-Severity of Illness Index, pubmed-meshheading:10952152-Thallium Radioisotopes, pubmed-meshheading:10952152-Tomography, Emission-Computed, Single-Photon
pubmed:year
2000
pubmed:articleTitle
Effects of metabolically ischemic, but viable, myocardium on QT dispersion in patients with acute myocardial infarction: a study with resting I-123-BMIPP/thallium-201 myocardial single-photon emission computed tomography.
pubmed:affiliation
First Department of Internal Medicine, Osaka City University Medical School, Osaka, Japan. hiroyuki@msic.med.osaka-cu.ac.jp
pubmed:publicationType
Journal Article