Linked Life Data

10952023

Source:http://linkedlifedata.com/resource/pubmed/id/10952023

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2000-11-13
pubmed:abstractText
The vast majority of patients with high-grade gliomas (HGG) over-express interleukin 4 (IL4)-independent binding sites for IL13 in situ. In addition, mutated IL13-based cytotoxins directed specifically toward glioma-associated sites are arguably the most active anti-glioma agents. Two IL13 receptor (R) proteins were identified: (1) IL13R alpha', a component of the signaling, heterodimeric high-affinity receptor for IL13 that is shared with IL4, and (2) IL13R alpha, a monomeric, IL4-independent receptor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1076-1551
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
440-9
pubmed:dateRevised
2008-11-20
pubmed:meshHeading
pubmed-meshheading:10952023-Adult, pubmed-meshheading:10952023-Brain, pubmed-meshheading:10952023-Brain Neoplasms, pubmed-meshheading:10952023-Cell Line, pubmed-meshheading:10952023-Fetus, pubmed-meshheading:10952023-Glioblastoma, pubmed-meshheading:10952023-Glioma, pubmed-meshheading:10952023-Humans, pubmed-meshheading:10952023-Interleukin-13, pubmed-meshheading:10952023-Interleukin-13 Receptor alpha1 Subunit, pubmed-meshheading:10952023-Male, pubmed-meshheading:10952023-Organ Specificity, pubmed-meshheading:10952023-Protein Subunits, pubmed-meshheading:10952023-Receptors, Interleukin, pubmed-meshheading:10952023-Receptors, Interleukin-13, pubmed-meshheading:10952023-Receptors, Interleukin-4, pubmed-meshheading:10952023-Reference Values, pubmed-meshheading:10952023-Testis, pubmed-meshheading:10952023-Transcription, Genetic, pubmed-meshheading:10952023-Tumor Cells, Cultured
pubmed:year
2000
pubmed:articleTitle
Molecular expression analysis of restrictive receptor for interleukin 13, a brain tumor-associated cancer/testis antigen.
pubmed:affiliation
Department of Surgery, Pennsylvania State University College of Medicine, Hershey 17033-0850, USA. wdebinski@psghs.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't