Source:http://linkedlifedata.com/resource/pubmed/id/10950782
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-11-3
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pubmed:abstractText |
An investigation was performed after an outbreak of bartonellosis in a region of Peru nonendemic for this disorder. Symptoms of acute and chronic bartonellosis were recorded. Serological analysis was performed on 55% of the affected population (554 individuals), 77.5% of whom demonstrated previous infection with Bartonella bacilliformis. The attack rate of Oroya fever was 13.8% (123 cases); the case-fatality rate was 0.7%. The attack rate of verruga peruana was 17.6%. A new specific immunostain was developed and used to confirm the presence of B. bacilliformis in the biopsied skin lesions. Most seropositive individuals (56%) were asymptomatic. The symptoms that were associated with prior infection, as determined by Western blot, included fever (37.2% of the seropositive vs. 17.2% of the seronegative population; P<.001), bone and joint pain (27% vs. 9%; P<.001), headache (27% vs. 12.3%; P <.001), and skin lesions described as verruga peruana (26.8% vs. 4.9%; P<.001). Our findings suggest that infection with B. bacilliformis causes a broad spectrum of disease that is significantly milder in severity than that frequently reported.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1899
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
182
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
865-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10950782-Adolescent,
pubmed-meshheading:10950782-Adult,
pubmed-meshheading:10950782-Animals,
pubmed-meshheading:10950782-Bartonella,
pubmed-meshheading:10950782-Bartonella Infections,
pubmed-meshheading:10950782-Child,
pubmed-meshheading:10950782-Educational Status,
pubmed-meshheading:10950782-Female,
pubmed-meshheading:10950782-Humans,
pubmed-meshheading:10950782-Humidity,
pubmed-meshheading:10950782-Male,
pubmed-meshheading:10950782-Peru,
pubmed-meshheading:10950782-Rabbits,
pubmed-meshheading:10950782-Skin,
pubmed-meshheading:10950782-Temperature
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pubmed:year |
2000
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pubmed:articleTitle |
Natural history of infection with Bartonella bacilliformis in a nonendemic population.
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pubmed:affiliation |
Department of Internal Medicine, Harbor-University of California Los Angeles Medical Center, Torrance, California, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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