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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1975-9-9
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pubmed:abstractText |
Meningococcal antigen was measured by countercurrent immunoelectrophoresis in the blood and cerebrospinal fluid of 200 patients with group A meningococcal meningitis. Antigen was detected in the blood of 27 (13.5 per cent) patients. These patients had a worse prognosis and a higher incidence of allergic complications, such as arthritis and vasculitis, about 5 days after the start of antibiotic treatment. Antigen was found in the CSF of 129 (67.5 per cent) patients); antigen often persisted in the cerebrospinal fluid despite antibiotic treatment before admission. A combination of immunoelectrophoresis and routine bacteriologic study was used in the diagnosis of 162 (84.8 per cent) patients with meningococcal meningitis. High levels of antigen and a slow antigen disappearance were associated with neurologic damage. The antigen is stable and may be detected from specimens of cerebrospinal fluid dried on filter paper.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0002-9343
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pubmed:author |
pubmed-author:BRYCESONA DAD,
pubmed-author:BruetonMM,
pubmed-author:DavidsonNN,
pubmed-author:DugganMM,
pubmed-author:GreenwoodB MBM,
pubmed-author:OomenJ MJM,
pubmed-author:ParryE HEH,
pubmed-author:RajkovicA DAD,
pubmed-author:TomkinsAA,
pubmed-author:TugwellPP,
pubmed-author:WarrellD ADA,
pubmed-author:WhittleH CHC,
pubmed-author:ZalinAA
|
pubmed:issnType |
Print
|
pubmed:volume |
58
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
823-8
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:1094829-Antigens, Bacterial,
pubmed-meshheading:1094829-Chloramphenicol,
pubmed-meshheading:1094829-Clinical Trials as Topic,
pubmed-meshheading:1094829-Humans,
pubmed-meshheading:1094829-Immunoelectrophoresis,
pubmed-meshheading:1094829-Length of Stay,
pubmed-meshheading:1094829-Meningococcal Infections,
pubmed-meshheading:1094829-Penicillins,
pubmed-meshheading:1094829-Prognosis,
pubmed-meshheading:1094829-Sulfonamides
|
pubmed:year |
1975
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pubmed:articleTitle |
Meningococcal antigen in diagnosis and treatment of group A meningococcal infections.
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pubmed:publicationType |
Journal Article,
Clinical Trial
|