10944562

Source:http://linkedlifedata.com/resource/pubmed/id/10944562

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0002395, umls-concept:C0006104, umls-concept:C0035647, umls-concept:C0449774, umls-concept:C1879547
pubmed:issue	7
pubmed:dateCreated	2000-8-17
pubmed:abstractText	The epsilon4 allele of the apolipoprotein E gene (APOE) is the chief known genetic risk factor for Alzheimer's disease, the most common cause of dementia late in life. To determine the relation between brain responses to tasks requiring memory and the genetic risk of Alzheimer's disease, we performed APOE genotyping and functional magnetic resonance imaging (MRI) of the brain in older persons with intact cognition.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/AG10123, http://linkedlifedata.com/resource/pubmed/grant/AG13308, http://linkedlifedata.com/resource/pubmed/grant/MH52453, http://linkedlifedata.com/resource/pubmed/grant/P30 AG010123-03, http://linkedlifedata.com/resource/pubmed/grant/P50 AG005128-21, http://linkedlifedata.com/resource/pubmed/grant/P60 AG011268-07, http://linkedlifedata.com/resource/pubmed/grant/R01 AG013308-13, http://linkedlifedata.com/resource/pubmed/grant/R01 MH052453-05, http://linkedlifedata.com/resource/pubmed/grant/R01 NS031153-14
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0255562
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein E3, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoprotein E4, http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E
pubmed:status	MEDLINE
pubmed:month	Aug
pubmed:issn	0028-4793
pubmed:author	pubmed-author:BookheimerS YSY, pubmed-author:CohenM SMS, pubmed-author:MazziottaJ CJC, pubmed-author:Pericak-VanceM AMA, pubmed-author:SaundersA MAM, pubmed-author:SmallG WGW, pubmed-author:StrojwasM HMH
pubmed:issnType	Print
pubmed:day	17
pubmed:volume	343
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	450-6
pubmed:dateRevised	2011-9-26
pubmed:meshHeading	pubmed-meshheading:10944562-Aged, pubmed-meshheading:10944562-Aged, 80 and over, pubmed-meshheading:10944562-Alleles, pubmed-meshheading:10944562-Alzheimer Disease, pubmed-meshheading:10944562-Apolipoprotein E3, pubmed-meshheading:10944562-Apolipoprotein E4, pubmed-meshheading:10944562-Apolipoproteins E, pubmed-meshheading:10944562-Brain, pubmed-meshheading:10944562-Brain Mapping, pubmed-meshheading:10944562-Female, pubmed-meshheading:10944562-Heterozygote, pubmed-meshheading:10944562-Hippocampus, pubmed-meshheading:10944562-Humans, pubmed-meshheading:10944562-Image Processing, Computer-Assisted, pubmed-meshheading:10944562-Magnetic Resonance Imaging, pubmed-meshheading:10944562-Male, pubmed-meshheading:10944562-Memory, pubmed-meshheading:10944562-Middle Aged, pubmed-meshheading:10944562-Neuropsychological Tests
pubmed:year	2000
pubmed:articleTitle	Patterns of brain activation in people at risk for Alzheimer's disease.
pubmed:affiliation	Department of Psychiatry and Biobehavioral Sciences, and the Brain Mapping Center, University of California, Los Angeles, USA.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't