Source:http://linkedlifedata.com/resource/pubmed/id/10942063
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
2001-3-8
|
pubmed:abstractText |
The cytotoxic agent bendamustine combines a purine-like benzimidazol and alkylating nitrogen mustard group. The clinically tolerated dose for single bolus bendamustine is 215 mg/m2, for fractionated therapy on four consecutive days 85 mg/m2. The maximum tolerated dose of a day 1 and 8 (q4w) 30 min infusion schedule was recently found to be 160 mg/m2, mouth dryness and fatigue were dose-limiting. Our current phase I trial was designed to define the recommended dose of a new weekly short infusion schedule.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0923-7534
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
11
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
729-34
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:10942063-Adult,
pubmed-meshheading:10942063-Antineoplastic Agents,
pubmed-meshheading:10942063-Drug Administration Schedule,
pubmed-meshheading:10942063-Female,
pubmed-meshheading:10942063-Humans,
pubmed-meshheading:10942063-Infusions, Intravenous,
pubmed-meshheading:10942063-Life Expectancy,
pubmed-meshheading:10942063-Lymphocyte Count,
pubmed-meshheading:10942063-Male,
pubmed-meshheading:10942063-Maximum Tolerated Dose,
pubmed-meshheading:10942063-Middle Aged,
pubmed-meshheading:10942063-Neoplasm Staging,
pubmed-meshheading:10942063-Neoplasms,
pubmed-meshheading:10942063-Nitrogen Mustard Compounds
|
pubmed:year |
2000
|
pubmed:articleTitle |
Weekly administration of bendamustine: a phase I study in patients with advanced progressive solid tumours.
|
pubmed:affiliation |
Department of Haematology/Oncology, Hannover Medical School, Germany. Schoeffski.Patrick@MH-Hannover.de
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Clinical Trial, Phase I
|