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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0020289,
umls-concept:C0021745,
umls-concept:C0021758,
umls-concept:C0023545,
umls-concept:C0026473,
umls-concept:C0035647,
umls-concept:C0086418,
umls-concept:C0185117,
umls-concept:C0268731,
umls-concept:C0851285,
umls-concept:C1882911,
umls-concept:C2347946,
umls-concept:C2729610,
umls-concept:C2911684
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pubmed:issue |
4-5
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|
pubmed:dateCreated |
2000-9-6
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|
pubmed:abstractText |
Leukotriene A(4) (LTA(4)) hydrolase catalyzes the final step in the synthesis of leukotriene B(4) (LTB(4)). TH-1- and TH-2-derived cytokines may regulate LTB(4) synthesis by monocytes through their actions on the expression of LTA(4) hydrolase.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-7782
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 1999 S. Karger AG, Basel
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
258-65
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10940725-Blotting, Northern,
pubmed-meshheading:10940725-Blotting, Western,
pubmed-meshheading:10940725-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:10940725-Epoxide Hydrolases,
pubmed-meshheading:10940725-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:10940725-Glomerulonephritis,
pubmed-meshheading:10940725-Humans,
pubmed-meshheading:10940725-Interferon-gamma,
pubmed-meshheading:10940725-Interleukin-13,
pubmed-meshheading:10940725-Interleukin-4,
pubmed-meshheading:10940725-Leukotriene B4,
pubmed-meshheading:10940725-Monocytes,
pubmed-meshheading:10940725-RNA, Messenger
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|
pubmed:articleTitle |
Reciprocal regulation of LTA(4) hydrolase expression in human monocytes by gamma-interferon and interleukins 4 and 13: potential relevance to leukotriene regulation in glomerular disease.
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pubmed:affiliation |
Center for Glomerulonephritis, Renal Division, Emory University, Atlanta, GA 30033, USA. amonter@emory.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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