Source:http://linkedlifedata.com/resource/pubmed/id/10939605
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2000-8-16
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pubmed:abstractText |
Radiolabeled antibodies generated against tumor-associated antigens are used for immunoscintigraphy to detect tumors and tumor metastases. Although successful tumor imaging has been achieved using trace-labeled murine monoclonal antibodies, such antibodies often lead to the development of human anti-murine antibodies (HAMA), which limit their subsequent administration for tumor imaging and therapy. It has been reported recently that chicken polyclonal antibodies have high affinity and specificity for the antigen against which they are raised and do not have any immunological cross-reactivity with HAMA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-8916
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
86
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
233-7
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pubmed:dateRevised |
2008-12-12
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pubmed:meshHeading |
pubmed-meshheading:10939605-Animals,
pubmed-meshheading:10939605-Antibodies,
pubmed-meshheading:10939605-Antigen-Antibody Reactions,
pubmed-meshheading:10939605-Ascites,
pubmed-meshheading:10939605-Chickens,
pubmed-meshheading:10939605-Disease Models, Animal,
pubmed-meshheading:10939605-Immunoglobulin G,
pubmed-meshheading:10939605-Lymphoma,
pubmed-meshheading:10939605-Mice,
pubmed-meshheading:10939605-Radioimmunodetection,
pubmed-meshheading:10939605-Technetium,
pubmed-meshheading:10939605-Time Factors,
pubmed-meshheading:10939605-Tissue Distribution
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pubmed:articleTitle |
Preliminary study on immunoscintigraphy of a murine lymphoma using technetium-99M labeled chicken antibody.
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pubmed:affiliation |
Department of Biochemistry, Institute of Bioinorganic and Radiopharmaceutical Chemistry, Forschungszentrum Rossendorf, Dresden, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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