Linked Life Data

10938923

Source:http://linkedlifedata.com/resource/pubmed/id/10938923

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2000-12-12
pubmed:abstractText
BACKGROUND AND OBJECTIVES: Immune functions are impaired after allogeneic stem cell transplantation for several months depending on the age of the recipient, initial pathology, degree of HLA and minor histocompatibility antigens mismatches, origin and manipulation of the graft (unmanipulated or T-cell depleted bone marrow transplantation, cord blood) and post-transplantation events (acute or chronic graft-versus-host disease, relapse and infectious complications). MATERIAL AND METHODS, RESULTS AND CONCLUSION: In addition to lymphocyte phenotyping and functional assays, new tools are now available to monitor specific aspects of the immune response in the follow-up of hematopoietic stem cell transplantation: reconstitution of T cell diversity (spectratyping or Immunoscope), thymic function (TREC or "T-cell receptor rearrangement excision DNA circles") and antigen-specific T cell responses (HLA tetramers).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0042-9007
pubmed:author
pubmed:issnType
Print
pubmed:volume
78 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-31
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2000
pubmed:articleTitle
New tools in assessing immune reconstitution after hematopoietic stem cell transplantation.
pubmed:affiliation
Laboratoire d'Immunologie et d'Histocompatibilité, INSERM U. 396, Centre G. Hayem Hôpital Saint-Louis, Paris, France.
pubmed:publicationType
Journal Article, Review