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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2000-8-23
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pubmed:abstractText |
Brain contrast-enhanced MR imaging reflects the leakage of contrast material into the brain tissue due to blood-brain barrier (BBB) disruption. The contact between brain tissue and contrast material requires a high level of neurotolerability of the contrast agent (CA). In the present study, we investigated the neurotolerability of the paramagnetic CA gadobenate dimeglumine, locally applied into the corpus striatum of freely moving rats, by evaluating its potential effects on cerebral glucose metabolism based on lactate levels.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0284-1851
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
394-9
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:10937766-Animals,
pubmed-meshheading:10937766-Brain,
pubmed-meshheading:10937766-Contrast Media,
pubmed-meshheading:10937766-Corpus Striatum,
pubmed-meshheading:10937766-Gadolinium,
pubmed-meshheading:10937766-Glucose,
pubmed-meshheading:10937766-Lactic Acid,
pubmed-meshheading:10937766-Male,
pubmed-meshheading:10937766-Meglumine,
pubmed-meshheading:10937766-Microdialysis,
pubmed-meshheading:10937766-Organometallic Compounds,
pubmed-meshheading:10937766-Rats,
pubmed-meshheading:10937766-Rats, Sprague-Dawley
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pubmed:year |
2000
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pubmed:articleTitle |
Gadobenate dimeglumine and cerebral glucose metabolism. Continuous monitoring of striatal lactate levels in freely moving rats.
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pubmed:affiliation |
Milano Research Centre, Bracco SpA, Milan, Italy.
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pubmed:publicationType |
Journal Article
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