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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2000-12-6
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pubmed:abstractText |
A one-pot total synthesis of aspergillamide and analogues by a solution phase Ugi multi component reaction (MCR) is described. The reaction is easily performed in 96-well plates and offers a facile access to diverse aspergillamide analogue compound libraries. The antibiotic and cytotoxic activity of these compounds is measured. Several of them are more potent than the natural product.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
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pubmed:month |
Aug
|
|
pubmed:issn |
0960-894X
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pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
7
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
|
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pubmed:pagination |
1701-5
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|
pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
|
|
pubmed:year |
2000
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|
pubmed:articleTitle |
One-pot synthesis and biological evaluation of aspergillamides and analogues.
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pubmed:affiliation |
Morphochem AG, München, Germany.
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|
pubmed:publicationType |
Journal Article
|
