To investigate whether chronic administration of the long-acting glucagon-like peptide-1 receptor agonist exendin-4 can elicit sustained reductions in food intake and body weight and whether its actions require an intact leptin system.
SmithKline Beecham Pharmaceuticals, Department of Vascular Biology, New Frontiers Science Park, Harlow, Essex, United Kingdom. kamal_A_Al-Barazanji@sbphrd.com