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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1975-7-14
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pubmed:abstractText |
Chromatin prepared by gentle methods from mouse myeloma cells retained its ability to synthesize RNA using bound endogenous RNA polymerase (RNA nucleotidyltransferase; nucleosidetriphosphate:RNA nucleotidyltransferase, EC 2.7.7.6). The transcription resembles that observed in vivo in several respects. The low-molecular-weight RNA species 5S RNA and the 4.5S precursor to 4S RNA, are transcribed accurately and transcription is reinitiated continually in vitro. Their synthesis was not inhibited by alpha-amanitin (1 mug/ml) as was found previously for these species in isolated nuclei.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4108111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4315151,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4357875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4364529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4365372,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4370472,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4516203,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4525293,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4558099,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4583315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4587253,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4587403,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4587751,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4731189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4855627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4857734,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-4859572,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5021308,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5083146,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5289255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5476920,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5718554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/1093165-5832284
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Chromatin,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Directed RNA Polymerases,
http://linkedlifedata.com/resource/pubmed/chemical/Myeloma Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nucleic Acid Precursors,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Ribosomal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Transfer
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
72
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1082-6
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pubmed:dateRevised |
2010-9-3
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pubmed:meshHeading |
pubmed-meshheading:1093165-Animals,
pubmed-meshheading:1093165-Cell Line,
pubmed-meshheading:1093165-Chromatin,
pubmed-meshheading:1093165-DNA, Neoplasm,
pubmed-meshheading:1093165-DNA-Directed RNA Polymerases,
pubmed-meshheading:1093165-Escherichia coli,
pubmed-meshheading:1093165-Molecular Weight,
pubmed-meshheading:1093165-Myeloma Proteins,
pubmed-meshheading:1093165-Nucleic Acid Hybridization,
pubmed-meshheading:1093165-Nucleic Acid Precursors,
pubmed-meshheading:1093165-RNA, Neoplasm,
pubmed-meshheading:1093165-RNA, Ribosomal,
pubmed-meshheading:1093165-RNA, Transfer,
pubmed-meshheading:1093165-Transcription, Genetic,
pubmed-meshheading:1093165-Xenopus
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pubmed:year |
1975
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pubmed:articleTitle |
Chromatin directed transcription of 5S and tRNA genes.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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