|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2000-9-6
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|
pubmed:abstractText |
The E-cadherin-catenin complex plays a crucial role in epithelial cell-cell adhesion and in the maintenance of tissue architecture. Perturbation in the expression or function of this complex results in loss of intercellular adhesion, with possible consequent cell transformation and tumour progression. Recently, much progress has been made in understanding the interaction between the different components of this protein complex and how this cell-cell adhesion complex is modulated in cancer cells.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Aug
|
|
pubmed:issn |
0007-1323
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
87
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
992-1005
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:10931041-Animals,
pubmed-meshheading:10931041-Cadherins,
pubmed-meshheading:10931041-Cell Adhesion,
pubmed-meshheading:10931041-Cytoskeletal Proteins,
pubmed-meshheading:10931041-Dogs,
pubmed-meshheading:10931041-Genes, APC,
pubmed-meshheading:10931041-Humans,
pubmed-meshheading:10931041-Mutation,
pubmed-meshheading:10931041-Neoplasm Proteins,
pubmed-meshheading:10931041-Neoplasms,
pubmed-meshheading:10931041-Proto-Oncogene Proteins,
pubmed-meshheading:10931041-Trans-Activators,
pubmed-meshheading:10931041-Wnt Proteins,
pubmed-meshheading:10931041-Zebrafish Proteins,
pubmed-meshheading:10931041-beta Catenin
|
|
pubmed:year |
2000
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|
pubmed:articleTitle |
E-cadherin-catenin cell-cell adhesion complex and human cancer.
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|
pubmed:affiliation |
Departments of Surgery and Pathology, Erasmus University Medical Centre, Rotterdam, The Netherlands.
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|
pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|
