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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2000-8-22
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pubmed:abstractText |
Proliferation and migration of hepatic stellate cells (HSCs) and expression of chemokines are involved in the pathogenesis of liver inflammation and fibrogenesis. Peroxisome proliferator-activated receptor (PPAR)-gamma is a receptor transcription factor that controls growth and differentiation in different tissues. We explored the effects of PPAR-gamma agonists on the biological actions of cultured human HSCs.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/15-deoxy-delta(12,14)-prostaglandin...,
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chromans,
http://linkedlifedata.com/resource/pubmed/chemical/Cytotoxins,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Mitogen-Activated Protein Kinases,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet-Derived Growth Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Prostaglandin D2,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazoles,
http://linkedlifedata.com/resource/pubmed/chemical/Thiazolidinediones,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Tyrosine,
http://linkedlifedata.com/resource/pubmed/chemical/p38 Mitogen-Activated Protein...,
http://linkedlifedata.com/resource/pubmed/chemical/troglitazone
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:BatignaniGG,
pubmed-author:BonacchiAA,
pubmed-author:CaligiuriAA,
pubmed-author:CaporaleRR,
pubmed-author:EfsenEE,
pubmed-author:GentiliniPP,
pubmed-author:LaffiGG,
pubmed-author:MarraFF,
pubmed-author:PastacaldiSS,
pubmed-author:PinzaniMM,
pubmed-author:RomanelliR GRG
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pubmed:issnType |
Print
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pubmed:volume |
119
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
466-78
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:10930382-Antineoplastic Agents,
pubmed-meshheading:10930382-Biological Transport,
pubmed-meshheading:10930382-Cell Division,
pubmed-meshheading:10930382-Cell Movement,
pubmed-meshheading:10930382-Cell Survival,
pubmed-meshheading:10930382-Cells, Cultured,
pubmed-meshheading:10930382-Chemokine CCL2,
pubmed-meshheading:10930382-Chromans,
pubmed-meshheading:10930382-Cytotoxins,
pubmed-meshheading:10930382-Gene Expression,
pubmed-meshheading:10930382-Hepatitis,
pubmed-meshheading:10930382-Humans,
pubmed-meshheading:10930382-Interleukin-1,
pubmed-meshheading:10930382-Ligands,
pubmed-meshheading:10930382-Liver,
pubmed-meshheading:10930382-Liver Cirrhosis,
pubmed-meshheading:10930382-Mitogen-Activated Protein Kinases,
pubmed-meshheading:10930382-NF-kappa B,
pubmed-meshheading:10930382-Phosphorylation,
pubmed-meshheading:10930382-Platelet-Derived Growth Factor,
pubmed-meshheading:10930382-Prostaglandin D2,
pubmed-meshheading:10930382-Proto-Oncogenes,
pubmed-meshheading:10930382-RNA, Messenger,
pubmed-meshheading:10930382-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:10930382-Thiazoles,
pubmed-meshheading:10930382-Thiazolidinediones,
pubmed-meshheading:10930382-Transcription Factor AP-1,
pubmed-meshheading:10930382-Transcription Factors,
pubmed-meshheading:10930382-Tyrosine,
pubmed-meshheading:10930382-Wound Healing,
pubmed-meshheading:10930382-p38 Mitogen-Activated Protein Kinases
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pubmed:year |
2000
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pubmed:articleTitle |
Ligands of peroxisome proliferator-activated receptor gamma modulate profibrogenic and proinflammatory actions in hepatic stellate cells.
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pubmed:affiliation |
Dipartimento di Medicina Interna, Università di Firenze, Florence, Italy. f.marra@dfc.unifi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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