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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3A
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pubmed:dateCreated |
2000-8-17
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pubmed:abstractText |
The aim of this study was to enhance selectively the immunostimulatory properties of tumor cells. Based on their oncotropic properties, we used autonomous recombinant parvoviruses to transduce the genes coding for the constimulatory molecules CD80 (B7-1) or CD86 (B7-2) specifically into tumor cells without transducing normal cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD80,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD86,
http://linkedlifedata.com/resource/pubmed/chemical/CD86 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Cd86 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins
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pubmed:status |
MEDLINE
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pubmed:issn |
0250-7005
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1825-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:10928114-Animals,
pubmed-meshheading:10928114-Antigens, CD,
pubmed-meshheading:10928114-Antigens, CD80,
pubmed-meshheading:10928114-Antigens, CD86,
pubmed-meshheading:10928114-Cell Line, Transformed,
pubmed-meshheading:10928114-Female,
pubmed-meshheading:10928114-Flow Cytometry,
pubmed-meshheading:10928114-Gene Expression,
pubmed-meshheading:10928114-Gene Transfer Techniques,
pubmed-meshheading:10928114-Genetic Vectors,
pubmed-meshheading:10928114-Humans,
pubmed-meshheading:10928114-Mastocytosis,
pubmed-meshheading:10928114-Membrane Glycoproteins,
pubmed-meshheading:10928114-Mice,
pubmed-meshheading:10928114-Mice, Inbred CBA,
pubmed-meshheading:10928114-Parvoviridae Infections,
pubmed-meshheading:10928114-Parvovirus,
pubmed-meshheading:10928114-Protein Engineering,
pubmed-meshheading:10928114-Transduction, Genetic,
pubmed-meshheading:10928114-Tumor Cells, Cultured,
pubmed-meshheading:10928114-Virus Replication
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pubmed:articleTitle |
Oncoselective transduction of CD80 and CD86 in tumor cell lines using an autonomous recombinant parvovirus.
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pubmed:affiliation |
Molecular Biology Department, Université Libre de Bruxelles, Belgium.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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