Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5480
pubmed:dateCreated
2000-8-16
pubmed:databankReference
pubmed:abstractText
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants. Here, we report the same toc1 effect in the absence of light input to the clock. We also show that TOC1 controls photoperiodic flowering response through clock function. The TOC1 gene was isolated and found to encode a nuclear protein containing an atypical response regulator receiver domain and two motifs that suggest a role in transcriptional regulation: a basic motif conserved within the CONSTANS family of transcription factors and an acidic domain. TOC1 is itself circadianly regulated and participates in a feedback loop to control its own expression.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
4
pubmed:volume
289
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
768-71
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:10926537-Amino Acid Motifs, pubmed-meshheading:10926537-Amino Acid Sequence, pubmed-meshheading:10926537-Arabidopsis, pubmed-meshheading:10926537-Arabidopsis Proteins, pubmed-meshheading:10926537-Biological Clocks, pubmed-meshheading:10926537-Circadian Rhythm, pubmed-meshheading:10926537-Cloning, Molecular, pubmed-meshheading:10926537-DNA-Binding Proteins, pubmed-meshheading:10926537-Feedback, pubmed-meshheading:10926537-Gene Expression Regulation, Plant, pubmed-meshheading:10926537-Genes, Plant, pubmed-meshheading:10926537-Molecular Sequence Data, pubmed-meshheading:10926537-Mutation, Missense, pubmed-meshheading:10926537-Phenotype, pubmed-meshheading:10926537-Photoperiod, pubmed-meshheading:10926537-Plant Proteins, pubmed-meshheading:10926537-Plants, Genetically Modified, pubmed-meshheading:10926537-RNA, Messenger, pubmed-meshheading:10926537-RNA, Plant, pubmed-meshheading:10926537-Repetitive Sequences, Amino Acid, pubmed-meshheading:10926537-Transcription, Genetic, pubmed-meshheading:10926537-Transcription Factors
pubmed:year
2000
pubmed:articleTitle
Cloning of the Arabidopsis clock gene TOC1, an autoregulatory response regulator homolog.
pubmed:affiliation
Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.