|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007382,
umls-concept:C0007586,
umls-concept:C0007600,
umls-concept:C0007634,
umls-concept:C0008633,
umls-concept:C0012863,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0043119,
umls-concept:C0043309,
umls-concept:C0079396,
umls-concept:C0205263,
umls-concept:C1883709,
umls-concept:C2349975
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2000-8-10
|
|
pubmed:abstractText |
To investigate whether catalytic topoisomerase II activity by ICRF187, a compound that interferes with the catalytic cycle of topoisomerase II without causing DNA damage, could result in a modulation of X-ray-induced chromosomal damage in Werner's syndrome (WS) cell lines.
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|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jul
|
|
pubmed:issn |
0955-3002
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
76
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
913-22
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
|
|
pubmed:year |
2000
|
|
pubmed:articleTitle |
Catalytic inhibition of topoisomerase II in Werner's syndrome cell lines enhances chromosomal damage induced by X-rays in the G2 phase of the cell cycle.
|
|
pubmed:affiliation |
Dipartimento di Agrobiologia ed Agrochimica Università degli Studi della Tuscia, Viterbo, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
